|
KMID : 0032220130250030360
|
|
Annals of Dermatology
2013 Volume.25 No. 3 p.360 ~ p.364
|
|
|
Generalized Dowling-Degos Disease: Case Reports
|
|
Wititsuwannakul Jade
Noppakun Nopadon
|
|
|
Abstract
|
|
|
|
Dowling-Degos disease (DDD) is a rare autosomal dominant trait characterized by numerous, symmetrical, progressive and pigmented macules over the axillae, groins, face, neck, arms and trunk as well as scattered comedo-like lesions (dark dot, follicles) and pitted acneiform scars. Histopathology is diagnostic testing using a distinctive form of acanthosis, characterized by an irregular elongation of thin branching rete ridges, with a concentration of melanin at the tips. We report cases of generalized DDD in a single family with autosomal dominant penetrance. DDD can be presented in a generalized form with hypopigmented lesions instead of reticulate hyperpigmentation confined to the flexor areas. This form can be differentiated from DUH by histopathology. (Ann Dermatol 25(3) 360∼364, 2013)
|
|
|
KEYWORD
|
|
|
Dowling-Degos disease, Pigmentary disorder, Reticulate
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|
|